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  • LifeVest
  • Innovations in LifeVest
    • zoll-life-vest

    Leading innovation in the WCD market

    With continuous innovation, enhancements for patient comfort, and growing recognition of the need for sudden cardiac death (SCD) protection for newly diagnosed heart failure patients with reduced ejection fraction, more clinicians and patients are choosing a LifeVest WCD today than ever before.1

         LifeVest Next Generation Garment details
    ZOLL LifeVest garment icon

    Next generation LifeVest garment: #1 in patient compliance
    LifeVest Next Generation Garment full view

    The most comfortable LifeVest ever

    With continuous innovation for patient comfort, the next generation LifeVest WCD garment marks the third advancement of the LifeVest system over the last five years. Patients rate the newest LifeVest® garment as more comfortable and easier to use2:

    • Lightweight, breathable performance wear fabrics
    • Flat seams, comfortable against the skin
    • Soft, double-plush straps
    • Largest range of patient garment sizes from 26"–56"

    20+ years of LifeVest design enhancements have led to a median real-world Wear Time® of 23.4+ hours/day.3,4,5 

    "The next generation LifeVest garment is a significant step forward in patient comfort and usability while maintaining market-leading clinical performance and safety. We are committed to continuous innovation to help patients feel confident while staying protected. Now, we’ve made the LifeVest garment even more comfortable.”

    Peter A. Brady, MD, Vice President of Clinical Affairs | ZOLL Cardiac Management Solutions

    Read More
    LifeVest compliance measurement from 2020 - 202

    Comfort you can measure with compliance

    • Best in class: LifeVest® ranks #1 in patient compliance at 23.4+ hours/day (median) based on peer-reviewed publications and real-world data.3,4,5
    • Recent data from SCD-PROTECT validates the safety and comfort of LifeVest, with an extremely low rate of inappropriate shocks (0.5% of patients) and discontinuation due to skin irritation (0.3% of patients).5
    • Now with a next generation garment, preferred for even greater comfort.2

    “It’s comfortable. It was extremely easy. People don’t even know you’re wearing it.”

    -Tanya, LifeVest patient
    AI-enhanced algorithm icon

    AI-enhanced algorithm
    Female LifeVest patient outside with friend

    Zero median false alarms at 90 days with advanced arrhythmia discrimination (AArD)6

    ZOLL® uses AI-based AArD technology to filter out non-physiological electrocardiogram (ECG) signals, reducing an already low rate of false alarms.

    • Zero median false alarms at a default threshold of 150bpm
    • Outcomes validated in a study of 96,000 real-world patients
    VIEW THE DATA
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    Only LifeVest has >140,000 patients in peer-reviewed publications

    LifeVest is the only WCD with:

    • 95% first shock success in peer-reviewed publications and real-world use7-10
    • 75% mortality reduction in a RCT per protocol11
    • 96% one-year survival12

    Results from the LifeVest RCT Trial

    The VEST Trial per-protocol analysis results demonstrated that patients that wore LifeVest realized significant mortality reductions in the first 90 days.
    Graph displaying ZOLL LifeVest data: Graph displaying ZOLL LifeVest data:
    WCD coverage icon

    Broad WCD coverage & the largest, most experienced support team
    Innovations in LifeVest_Assets_Stats_800x514_v4

    Patient access and support

    ZOLL has spent 20+ years building positive payer relationships and an extensive support network to help your patients with every step of their LifeVest journey:
    • The most comprehensive WCD coverage for Medicare, Medicaid, veterans, and commercial patients13
    • A range of financial programs provide access options for uninsured and underinsured patients
    • The largest, most experienced WCD support team
    • In-person training and support from representatives with extensive care experience
    • 24/7 multilingual support
    ZOLL LifeVest ECG Classifier icon

    See actionable arrhythmias with ECG Classifier
    Infographic showing that 1 in 14 patients experience an actionable arrhythmia during LifeVest use

    Highly accurate, FDA-approved classification of ECGs14

    1 in 14 patients experience an actionable arrhythmia during LifeVest use.7 Developed with machine learning, LifeVest ECG Classifier filters out noise and identifies arrhythmias that may require intervention — from ablation to ICD implant.

    See how ECGs captured by LifeVest enabled physicians to modify their patient’s treatment path.

    ECG CASE STUDIES
    LifeVest Patient engagement app icon

    The LifeVest Patient engagement app
    woman looking at phone screen which is displaying LifeVest Patient App data

    Education, data & support during recovery

    The LifeVest Patient App helps patients get the most out of their LifeVest experience.

    • Track progress with access to their own Wear Time® and Activity data.
    • On-demand device education, success stories, and support resources – all at your patients’ fingertips.
    Learn more about the LifeVest patient app

    1. Based on commercial data as of November 2025.

    2. Data on file, 20c1184_a01. Garment Comparative Wear Test.

    3. Data on file, 90d0258_a01. 2021 Commercial Compliance Analysis.

    4. Garcia R, Combes N, Defaye P, et al. Wearable cardioverter-defibrillator in patients with a transient risk of sudden cardiac death: the WEARIT-France cohort study. EP Europace. 2020;23(1):73-81. doi:10.1093/europace/euaa268

    5. David Duncker, Eloi Marijon, Marco Metra, Olivier Piot, Marat Fudim, Uwe Siebert, Norbert Frey, Lars Siegfried Maier, Johann Bauersachs, Sudden cardiac death in newly diagnosed non-ischaemic or ischaemic cardiomyopathy assessed with a wearable cardioverter-defibrillator: the German nationwide SCD-PROTECT study, European Heart Journal, 2025;, ehaf668, https://doi.org/10.1093/eurheartj/ehaf668

    6. Arkles J, Delaughter C, D’Souza B. A novel artificial intelligence based algorithm to reduce wearable cardioverter-defibrillator alarms. J Interv Cardiac Electrophysiol. 2023. https://doi.org/10.1007/s10840-023-01497-w
    7. Kutyifa V, Moss AJ, Klein H, et al. Use of the wearable cardioverter defibrillator in high-risk cardiac patients: Data from the prospective registry of patients using the wearable cardioverter defibrillator (WEARIT-II Registry). Circulation. 2015;132(17):1613–1619.
    8. Data on file, 90d0241_a01. Report of AArD Performance during 2019.
    9. Data on file, 90a0061_a01_revb. Clinical Evaluation Report for LifeVest Wearable Defibrillator, Model 4000, 2021.
    10. Chung MK, Szymkiewicz SJ, Shao M, Zishiri E, Niebauer MJ, Lindsay BD, & Tchou PJ (2010). Aggregate national experience with the  
      wearable cardioverter-defibrillator: Event rates, compliance, and survival. Journal of the American College of Cardiology, 56(3), 194–203.
    11. Olgin JE, Lee BK, Vittinghoff E, et al. Impact of wearable cardioverter-defibrillator compliance on outcomes in the VEST trial: As-treated and per-protocol analyses. J Cardiovasc Electrophysiol 2020;1–10. https://doi.org/10.1111/jce.14404
    12. Kutyifa V, Moss A, Klein H, et al. One-year follow-up of the prospective registry of patients using the wearable defibrillator (WEARIT-II Registry). Pacing Clin Electrophysiol. 2018;1–7. https://doi.org/10.1111/pace.13448
    13. Based on commercial data as of March 2025
    14. Pre-clinical test data on file at ZOLL as of July 2020.

    Contact a Product Expert

    ZOLL is ready to assist you in meeting your care goals. The team that has protected 1M+ LifeVest patients over 20+ years now provides a suite of solutions. Connect with an expert for personalized support.

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